Grandpa is moody, will his cognition decline? Predicting cognitive decline in Parkinson's disease from non-motor symptoms evolution
While Parkinson’s disease (PD) is recognized by its motor symptoms, it is also characterized by non-motor symptoms (NMS), such as anxiety, depression, pain, etc. NMS often precede cognitive decline, making them potential predictors of such decline. This project aims to investigate the longitudinal association between non-motor symptoms and cognitive and neural decline in patients with PD. Early identification of individuals at higher risk of cognitive decline through their NMS presentation can facilitate timely interventions.