Modulation of functional connectivity in Parkinson’s disease with neuropsychiatric symptoms
This project aims to investigate the functional connectivity patterns in individuals with Parkinson’s disease and neuropsychiatric symptoms (PD+NPS) compared to those without the NPS. The study utilizes resting-state fMRI data to analyze the connectivity matrix and identify alterations in functional brain networks associated with PD+NPS. The project also involves familiarizing with data science packages, interpreting neuroimaging data, and advanced visualization techniques. The findings may contribute to understanding the neural mechanisms underlying PD+NPS and inform future research and interventions. The project involves BIDS validation, fMRI preprocessing, functional connectivity analysis, group comparisons, and prediction modeling for mild cognitive impairment.