This project aims to investigate the functional connectivity patterns in individuals with Parkinson’s disease and neuropsychiatric symptoms (PD+NPS) compared to those without the NPS. The study utilizes resting-state fMRI data to analyze the connectivity matrix and identify alterations in functional brain networks associated with PD+NPS. The project also involves familiarizing with data science packages, interpreting neuroimaging data, and advanced visualization techniques. The findings may contribute to understanding the neural mechanisms underlying PD+NPS and inform future research and interventions. The project involves BIDS validation, fMRI preprocessing, functional connectivity analysis, group comparisons, and prediction modeling for mild cognitive impairment.
Does functional connectivity between brain regions differ in male and female? If yes then fMRI data can be used to distinguish sex on the basis of the difference in functional connectivity. I applied supervised Machine Learning algorithms on the fMRI data to classify sex.
This project aimed to understand how to pre-process fMRI data using fMRIPrep. Through this learning experience, a tutorial was created.
Computational Psychiatry is growing trend that applies machine learning methods to psychological disorders. How well can we predict schizophrenia diagnosis from brain activity? This project uses neuroimaging tools from Nilearn, and machine learning tools from scikit-learn to differentiate patients diagnosed with schizophrenia from healthy controls using resting state fmri data.